953 IMMUNOGENETICS OF JUVENILE DERMATOMYOSITIS (JDMS), A COLLABORATIVE STUDY
نویسندگان
چکیده
منابع مشابه
The role of etanercept in juvenile dermatomyositis (JDMS) in children
Introduction Juvenile dermatomyositis is a rare autoimmune disease characterised by profound muscle weakness in addition to skin lesions, calcinosis, and underlying vasculopathy. Current treatment plans, including methotrexate and corticosteroids, are ineffective in some patients and may be associated with significant adverse events. The benefits and risks of etanercept in JDMS are not well stu...
متن کاملJuvenile dermatomyositis: a case study.
38 Volume 25 Number 1 over the bridge of the nose along with a purplish rash over her eyelids that had been present for approximately 6 to 8 weeks. In addition, the child had a pruritic bumpy rash on her upper arms, elbows, knuckles, and knees and an elongated purplish area on her right shin. The child’s mother stated, “The facial rash seems to worsen after she has been in the sun.” The mother ...
متن کاملJuvenile Dermatomyositis: A Review
Juvenile dermatomyositis is a systemic vasculopathy, affecting mainly the skin and muscle. In the United States, it is seen in more than three per million children per year. It is diagnosed on the basis of the criteria set by Bohan and Peter. The following review describes the characteristic clinical manifestations, the pathophysiology and immunology of the disease. The various treatment modali...
متن کاملJuvenile dermatomyositis.
Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...
متن کاملJuvenile dermatomyositis.
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1981
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198104001-00978